c Principles of Pathologic Review (PM-A).
d Best supportive care is recommended for patients presenting with performance status (PS) 3–4. See Principles of Supportive Care and Survivorship (PM-B).
e Principles of Systemic Therapy (PM-C).
f Pleural intensity-modulated radiation therapy (IMRT) should only be performed in carefully selected patients at centers with experience in this technique. See Principles
of Radiation Therapy (PM-D).
g Observation may be considered for patients who are asymptomatic with minimal burden of disease if systemic therapy is planned at the time of symptomatic or
radiographic progression.
h The benefit of surgical resection in pleural mesothelioma is unclear and there is no evidence that patient survival is improved with surgery when combined with
systemic therapy versus systemic therapy alone.
i Principles of Supportive Care and Survivorship (PM-B).
