e Principles of Systemic Therapy (PM-C).
f Pleural IMRT should only be performed in carefully selected patients at centers with experience in this technique. See Principles of Radiation Therapy (PM-D).
h The benefit of surgical resection in pleural mesothelioma is unclear and there is no evidence that patient survival is improved with surgery when combined with
systemic therapy versus systemic therapy alone.
i Principles of Supportive Care and Survivorship (PM-B).
j If FDG-PET/CT is to be done, recommend obtaining FDG-PET/CT before pleurodesis. Confirm diagnosis of pleural mesothelioma prior to pleurodesis. If pleural
mesothelioma is suspected, consider evaluation by a multidisciplinary team with expertise in pleural mesothelioma.
k For further evaluation of possible chest, spinal, diaphragmatic, or vascular involvement based on CT imaging.
l Principles of Surgery (PM-E).
