s If MRI is not possible, CT of head with contrast.
mm Timing of CT scans within Guidelines parameters is a clinical decision.
nn FDG-PET/CT is currently not warranted in the routine surveillance and follow-up of patients with NSCLC. However, many benign conditions (such as atelectasis, consolidation, and radiation fibrosis) are difficult to differentiate from neoplasm on standard CT imaging, and FDG-PET/CT can be used to differentiate true malignancy in these settings. However, if FDG-PET/CT is to be used as a problem-solving tool in patients after RT, histopathologic confirmation of recurrent disease is needed when possible because persistent inflammatory hypermetabolism is common after prior RT. Increasing intensity and/or size of focal hypermetabolism over time is the most specific indicator of recurrence that warrants confirmation.
oo Examples of high-risk factors include, but are not limited to, EGFR mutations, ALK gene fusions, and node-positive disease. NCCN-NSCLC-2026V6 NCCN非小细胞肺癌指南导航
