i Methods for evaluation include mediastinoscopy, mediastinotomy, EBUS, EUS, and CT-guided biopsy. An EBUS-TBNA negative for malignancy in a clinically (FDGPET/CT and/or CT) positive mediastinum should undergo subsequent mediastinoscopy prior to surgical resection.
l FDG-PET/CT performed skull base to mid-thigh. Positive FDG-PET/CT scan findings for mediastinal nodal or distant disease need pathologic or other radiologic confirmation. If FDG-PET/CT scan is positive in the mediastinum, lymph node status needs pathologic confirmation.
s If MRI is not possible, CT of head with contrast.
jj Including selected patients with stage M1c and limited number and volume of metastatic lesions amenable to definitive local therapy. Clinical trials have included up to 3 to 5 metastatic sites.
kk NCCN：中枢神经系统肿瘤（Central Nervous System Cancers） .
n 手术治疗原则（NSCL-B）.
o 放射治疗原则（NSCL-C） .
p Image-guided thermal ablation (IGTA) therapy (eg, cryotherapy, microwave, radiofrequency) may be an option for select patients. 影像引导下热消融治疗原则（NSCL-D）.
w 同步放化疗方案（NSCL-F）.
cc Chest CT with contrast and/or FDG-PET/CT to evaluate progression.
ll Typically, RT (including SABR) or surgical resection. NCCN-NSCLC-2026V6 NCCN非小细胞肺癌指南导航
